Paul Klein may refer to:

  • Paul Klein (missionary) (born 1652), Czech Jesuit missionary in the Philippines, pharmacist and Cavite College rector, often referred to as Pablo Clain, or Paulus or Pavel Klein
  • Paul L. Klein (1929–98), developer of pay-per-view TV channels and creator of the least objectionable program theory
  • Paul Klein (chess player) (1915–1992), German–Ecuadorian chess player
  • Paul Klein (art activist) (born 1946), American art activist from Chicago

See also